Episode #5 Wolfram Syndrome with Dr. Sarah Gladstone

Dr. Sarah Gladstone joins the show to share her perspective of Wolfram Syndrome being a parent of a child with the condition and a physician.

Sarah Gladstone (She/Her) is a pediatrician who completed her MD at Vanderbilt University and pediatric residency at The Children’s Hospital of Boston prior to practicing in primary care for 15 years. She began working with WS researchers and parents to facilitate communication and help find a treatment for WS after her daughter was diagnosed with WFS1-Related Disorder in 2016. Sarah started the Unravel Wolfram Syndrome Fund to support WS research by Dr. Fumi Urano at Washington University in St. Louis. She joined forces with other WS parents to help create WSRA in 2020 and the Wolfram Syndrome Global Registry in 2022.

Dr. Gladstone is constantly intrigued by the connections that can be made between WS and other ER stress diseases and this inspires my continued search for repurposing of chaperones and small molecules to treat WS. She has met amazing researchers and parents who work with many different rare diseases as a result of comparing notes and progress in the rare disease treatment world.

Check out unravelwolframsyndrome.com and wsresearchalliance.org, both mentioned during the show.