November 15, 2020:

The relationship of the neuroinflammatory mechanism of glaucomatous neurodegeneration and the administration of NLY01.

https://www.cell.com/cell-reports/fulltext/S2211-1247%2820%2931260-2

November 12, 2020:

5 useful snacks to keep blood sugar under control.

https://food.ndtv.com/food-drinks/diabetes-diet-5-pre-lunch-snack-ideas-to-keep-your-blood-sugar-in-control-2306590

November 10, 2020:

The uses of Magnetic Resonance Imaging in finding biomarkers for neurodegenerative diseases.

https://www.eurekalert.org/pub_releases/2020-10/ibri-pap100720.php

Nov 2, 2020:

Link between diabetes and COVID-19 treatment.

https://www.cbs19news.com/story/42805974/research-finds-conditions-like-diabetes-may-impact-effectiveness-of-covid19-treatment

Our drug-repurposing clinical trial of dantrolene sodium in patients with Wolfram syndrome has been almost concluded. Nineteen patients could successfully complete the required six-month phase, and many of them decided to stay on dantrolene sodium another 18 months. The results of this open-label clinical trial (all the participants took dantrolene sodium) show that dantrolene sodium is well tolerated by patients with Wolfram syndrome. Although the study was small, a select few patients seemed to have improvements in diabetes-related outcomes, which might correlate with a positive trend in other outcome measures, including visual acuity and brain functions. This study justifies further investigation into using dantrolene sodium and other new drugs targeting the same molecular pathway for the treatment of Wolfram syndrome.

Depression and the link between cardiovascular disease in patients with type 2 diabetes.

https://www.sciencedirect.com/science/article/pii/S1056872720304785

 

A new podcast with Dr. Cal Roberts discussing tech and vision.

https://www.prnewswire.com/news-releases/lighthouse-guild-launches-new-podcast-series-on-tech–vision-with-dr-cal-roberts-301129669.html

The mental and financial impacts of disease on a family.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791092/

To further improve the clinical care for patients with Wolfram syndrome and Wolfram-related disorders, I have created a new genetics clinic at Center for Advanced Medicine, Washington University Medical Center. We offer genetic evaluations, education, and counseling for patients and family members of all ages with or suspected to have Wolfram syndrome or WFS1-related
disorders. We also provide personalized management plans based on the type of your gene variants together with other specialists at our medical center, such as Dr. Marshall, Dr. White, Dr. Hoekel, and beyond. To make an appointment with me, please call 314-747-7300 or 314-747-3294 (if you are participating in our research clinic/registry or interested in participating in the research). You can also send an email to WolframSyndrome@wustl.edu.

We could cover the costs for genetic testing if your insurance does not cover the entire amount of the costs.