International Wolfram Syndrome Partners

Université libre de Bruxelles, Center for Diabetes, Research

  • Mariana Igoillo Esteve, PhD – Mechanisms of Monogenic Diabetes, GLP-1 treatment for Wolfram syndrome
  • Miriam Cnop MD, PhD – Beta cell dysfunction and Monogenic Diabetes, GLP-1 clinical trial for Wolfram syndrome

KU Leuven

  • Geert Bultynck, PhD – Calcium signaling in WFS1 knockout cells (LCMS)
  • Lieve Moons, PhD – molecular mechanisms underlying neural circuit development, neuroinflammation, neuronal survival and regeneration
  • ​Jan Parys – Laboratory of Cellular and Molecular Signaling (LCMS)
  • Catherine Verfaillie, MD  – (SCIL) creating models for neurodegenerative disorders to allow study of mechanisms underlying neurodegeneration

University of Copenhagen

  • Lisbeth Tranebjærg, MD, PhD – ​Genetics of Wolfram syndrome

University of Tartu, Tartu, Estonia -Institute of Biomedicine and Translational Medicine

  • Mario Plaas, PhD – Rodent models of Wolfram syndrome, GLP-1 treatment for Wolfram syndrome
  • Anton Terasmaa, PhD – Rodent models of Wolfram syndrome, GLP-treatment for Wolfram syndrome
  • Eero Vasar, MD, PhD – Molecular mechanisms of Wolfram syndrome

Tartu University Children’s Hospital, Tartu, Estonia

  • Vallo Tillmann, MD – Diabetes and endocrine issues in Wolfram syndrome, Pediatric endocrinology

University of Helsinki, Finland

  • Mart Saarma, PhD – signaling and biological functions of GDNF family ligands and endoplasmic reticulum located CDNF/MANF neurotrophic factor families
  • Maria Lindahl, PhD

Institute of Neurosciences of Montpellier, University of Montpellier, Montpellier, France

  • Cécile Delettre, PhD – ER-mitochondria and Wolfram syndrome, mechanisms of visual impairment, gene therapy
  • Benjamin Delprat, PhD – ER-mitochondria and Wolfram syndrome, mechanisms of hearing impairment

Université Côte d’Azur, CHU, Inserm, CNRS, IRCAN, France

  • Véronique Paquis-Flucklinger,MD, PhD – Genetics of Wolfram syndrome
  • Laetitia Aubry, PhD – study of the therapeutic application potentials of iPSCs in Wolfram Syndrome

I-STEM – Evry, France

Centrum für Reproduktionsmedizin und Andrologie, ​WHO Kollaborationszentrum, EAA, Ausbildungszentrum, Universitätsklinikum Münster

  • Julia Rohayem, MD, PhD

Hadassah Medical Center

  • Gil Leibowitz, MD – Senior physician in Endocrinology and Metabolism, Beta-cell ER stress and function

Università degli Studi di Messina – Messina, Italy

  • Luciana Rigoli, MD – Departments of Pediatrics, Molecular Biology, Endocrinology

University of Yamaguchi

  • Yukio Tanizawa, MD, PhD – Biology of pancreatic Beta Cells, research in GLP-1 receptor signaling, ER stress and beta cell function

Medical University of Lodz

  • Wojciech Mlynarski, MD, PhD – Genetic forms of diabetes, head of Department of pediatric oncology, hematology and diabetology

Servicio Andaluz de Salud

  • ​Gema Esteban Bueno, MD

Laboratorio de Genética Molecular, IDIBELL, l’Hospitalet de Llobregat, Barcelona, Spain

  • Miguel López de Heredia, PhD
  • Virginia Nunes, PhD

University of Birmingham

  • Timothy Barrett, MD, PhD – leading an international randomised controlled trial of repurposed therapy in Wolfram syndrome, performs functional genetic studies and translational research with inherited forms of diabetes

University of Cambridge

  • Patrick Yu-Wai-Man – Academic neuro-ophthalmologist with specialist research interest in genetic treatment for mitochondrial eye disorders and WS vision loss