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AntiSense Oligonucleotides (ASOs), for the treatment of Wolfram syndrome by La Jolla Labs

La Jolla Labs, USA

  • Members of The Snow Foundation met with representatives from La Jolla Labs to investigate the role of RNA directed gene therapy, specifically AntiSense Oligonucleotides (ASOs), for the treatment of Wolfram syndrome.
  • La Jolla Labs undertook an investigation to determine the potential for ASO application, specifically for the treatment of autosomal dominant Wolfram-related disorder.
  • The head of research at LJL presented a review of the potential use of ASO therapy for WS based on disease biology and different ASO strategies.